Bob, a feckless bachelor, promised his mother that at her death he would care for his schizophrenic younger brother D.J. but he becomes apprehensive when the time comes. Facing up to his responsibility, Bob tries his best, but his set ways and D.J.'s erratic behavior mix like oil and water. Giving his promise one last shot, Bob takes D.J. on a fishing trip to the secluded lake where they vacationed as children. Here, the rush of memories transforms...

Follow the story of the challenging relationship between Billie and her younger schizophrenic sister, Elizabeth Baby. After their mother dies, Billie moves Baby in with her family. After a disturbing incident involving her son and Baby, it becomes clear to Billie that she cannot give her the care she needs.

"After her husband's death, immigrant mother Lily is left alone to look after her American-born son, Edward. At school, Edward is bullied, his grades plummet, and he hallucinates his dead father – and is diagnosed with schizophrenia. After Lily learns she has cancer, she hides it from Edward, while he secretly stops taking his medicine and manifests a video game character who urges him to shoot up his school. With Lily given a terminal diagnosis...

Gregorio is a schizophrenic young man with two great loves: his girlfriend Tania and his best friend Manuel. While Gregorio is isolated at psychiatric hospitals, Manuel and Tania began to meet secretly, and soon they start an affair.