The kingdom of Mathayus, the Scorpion King, has fallen and his queen lost to plague. Now an assassin for hire, he must defend a kingdom from an evil tyrant and his ghost warriors for the chance to regain the power and glory he once knew.

In the year 2707, war rages between Earth's four giant corporations as they battle over the planet's dwindling resources. Amid heavy combat, an errant shell shatters an ancient buried seal, releasing a horrific mutant army from its eternal prison deep within the Earth to fulfill the ages-old prophesy and save mankind.